Anabact API and References

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Abridged Prescribing Information – Anabact 0.75% w/w Gel.

Please consult the full summary of product characteristics before prescribing.

Presentation: A pale yellow water-based clear gel containing 0.75% w/w metronidazole for topical application.

Uses: For the treatment of malodorous fungating tumours, gravitational ulcers and decubitus ulcers.

Dosage and Administration: Adults and Elderly: Clean the wound thoroughly. Apply the gel over the complete area and cover with a non-adherent dressing. Use once or twice daily until the odour has been completely eradicated. Children: Not recommended for children under 12 years of age.

Contra-indications: Known sensitivity to metronidazole, Bronopol, hydroxybenzoic acid esters, hydroxyethylcellulose, phosphoric acid or propylene glycol.

Special warnings and Precautions for Use: Strong sunlight should be avoided because metronidazole is unstable under ultraviolet light. Contact with the eyes should be avoided.

Anabact 0.75% w/w Gel contains Bronopol which can cause local skin reactions such as contact dermatitis; propylene glycol which may cause skin irritation, and hydroxybenzoic acid esters that may cause allergic reactions (possibly delayed).

Side Effects: Dryness of the skin, local stinging or irritation have been reported during treatment with metronidazole topical gel.

Legal category: POM.

NHS Price: 15g £5.64, 30g £7.89, 40g £15.89.

Marketing Authorisation Number: PL 16794/0006.

Marketing Authorisation Holder: Cambridge Healthcare Supplies Limited, Unit 1 Chestnut Drive, Wymondham, Norfolk, NR18 9SB.

Date of Preparation: September 2019.

Adverse events should be reported. Reporting forms and information can be found at www.mhra.gov.uk/yellowcard. Adverse events should also be reported to Cambridge Healthcare Supplies Limited.

References:

1.  Finlay. IG. et al. The effect of Topical 0.75% Metronidazole Gel on Malodorous Cutaneous Ulcers. J. Pain Symptom. 1996 11(3):158-162

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Anabact Gel is the only metronidazole gel specifically indicated for the deodorisation of fungating tumours, gravitational ulcers and decubitus ulcers, and is clinically proven to rapidly reduce pain and infection as well as discharge and odour1. Anabact Gel is included in many local and regional wound care formularies.

Metronidazole is an antibacterial agent which has been used for many years in the treatment of anaerobic infections.

As most topical Metronidazole gels are only licensed for the treatment of rosacea,
it is important to prescribe Anabact by brand name, if intending to use for fungating tumours or ulcers.

Anabact is available in 15g, 30g and 40g sizes for convenience of use and reduced wastage, and can be used with many standard non-medicated and non-adherent dressings.

Fungating tumours, pressure ulcers and other chronic wounds are frequently the source of offensive odours that distress patients, family and healthcare professionals2. The management of patients with a fungating wound is focused essentially upon symptom control and appropriate psychosocial support.

Infected Ulcers Button2 

Fungating Wounds Button 

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1 Finlay. IG. et al. The effect of Topical 0.75% Metronidazole Gel on Malodorous
Cutaneous Ulcers. J. Pain Symptom Management. 1996; 11(3): 158-162

2 Kalinski. C. et al. Effectiveness of a Topical Formulation Containing Metronidazole for Wound Odour and Exudate Control.
Online report http://www.woundsresearch.com/article/3950

THIS INFORMATION IS FOR HEALTHCARE PROFESSIONALS ONLY

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Anabact gel contains the active ingredient metronidazole and is used for the deodorisation of fungating tumours, gravitational ulcers and decubitous ulcers. The malodour is caused by infection; the anti-bacterial action of metronidazole eliminates the infection, thus helping to deodorise the smell.

For more information about tumours and ulcers please click here or consult your doctor.

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